Product Reference
Wnt proteins regulate acetylcholine receptor clustering in muscle cells.
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| Author |
Bin Zhang,Chuan Liang,Ryan Bates,Yiming Yin,Wen-Cheng Xiong,Lin Mei |
| Citation Information |
Molecular brain, 5: (2012) |
| Related Products |
05-1050 |
| Pub Med ID |
22309736 |
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Abstract
The neuromuscular junction (NMJ) is a cholinergic synapse that rapidly conveys signals from motoneurons to muscle cells and exhibits a high degree of subcellular specialization characteristic of chemical synapses. NMJ formation requires agrin and its coreceptors LRP4 and MuSK. Increasing evidence indicates that Wnt signaling regulates NMJ formation in Drosophila, C. elegans and zebrafish.
