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Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells.

   
Author Yi-Ming Ma,Yu-Bo Zhou,Chuan-Ming Xie,Dong-Mei Chen,Jia Li
Citation Information Acta pharmacologica Sinica, 33: (2012)
Keywords Apoptosis,Cell Line, Tumor,Coumarins,G2 Phase Cell Cycle Checkpoints,HeLa Cells,Humans,M Phase Cell Cycle Checkpoints,Microtubules
Related Products 05-368
Pub Med ID 22266726
   

Abstract

To identify a novel coumarin analogue with the highest anticancer activity and to further investigate its anticancer mechanisms.