Millipore Technical Publications |
 | ||
Guava Celltoxicity AssayFor easy, sensitive, single-cell based cytotoxicity measurements |
| Easy, accurate cytotoxicity
assesment Cytotoxicity has never been easier to assess than with the Guava Cell Toxicity Assay. This single-cell based assay provides results that are as good as the 51-Chromium release assay but without radioactivity. What’s more, the assay is more accurate and precise than population-based methods such as alamarBlue, MTT, and LDH. The Guava Cell Toxicity Assay provides all relevant statistics, including percentage of target cells killed, effector and target cell percentages, and whether the cells are alive or dead. CMC , CDC, ADCC , NK All of the common methods used to study cytotoxicity can be performed using the Guava Cell Toxicity Assay, including cell-mediated or cell-dependent cytotoxicity (CMC or CDC), antibody-dependent cell mediated cytotoxicity (ADCC), and natural killer cytotoxicity (NK). The assay uses a well-characterized cell tracking dye that is optimized for use on all Guava Systems. The dye diffuses freely into cells and is retained within the cell without affecting cellular function. Because the assay is both sensitive and reproducible, assay development time is reduced. Click the PDF above for the full document. | |
| |