Millipore Technical Publications |
 | TN- AN1044EN00 | |
Immunoglobulin Depletion from Serum Samples Using PureProteome Protein A and Protein G Magnetic Beads | ||
| Lit No: | AN1044EN00 | |
| Year: | 2009 | |
| The development of new clinical sample preparation tools has been driven by accelerated clinical proteomics research focused on the identification of biomarkers that ultimately can be used by clinicians for disease diagnosis, prognosis and personalized therapy. The ability to diagnose a cancer patient by analyzing the proteins circulating in the blood before formation of a detectable tumor can increase the patient’s chance of survival. Either an entire protein or one of its cleavage products, secreted from diseased cells into the bloodstream, can serve as a specific biomarker. Besides cancer diagnosis, the clinical application of biomarkers covers numerous other disease states including metabolic syndrome, diabetes, neurodegenerative disorders, with the types of clinical samples subjected to analysis varying widely. |
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