Millipore Technical Publications |
HESCA-1 and HESCA-2: Novel Antibodies for the Identification of Human Embryonic Stem Cells | ||
| Lit No: | AN1064EN00 | |
| Year: | 2008 | |
| Pluripotent human embryonic stem cells (hESCs) are a major focus of research because of their experimental utility and great promise in regenerative medicine. However, only a limited number of hESC cell lines have been approved for federally-funded research, and few tools are available for sufficiently defining pluripotent hESCs compared with more differentiated populations. Thus, the need for new monoclonal antibodies against cell surface markers for the further study of stem cells is evident. Using a proprietary platform for selecting hybridomas, we were able to label at least two antibodies that appear to label undifferentiated hESCs and thus may represent novel markers for pluripotency. Click the PDF above for the full document. | |

