 | UCOE (Ubiquitous Chromatin Opening Elements) technology
is a breakthrough solution for rapid protein production and
cell line development using mammalian systems. Using this
technology, researchers can obtain gram level quantities of
protein material from highly productive stable cell pools in
less than four weeks. Application of the UCOE technology to
the production of stable pools results in cultures containing
a larger percentage of highly expressing clones as compared
with pools generated with conventional non-UCOE vectors.
High yielding, stable cell lines can be derived in less than 60
days, screening less than 100 clones, and without the need
for amplification. UCOE technology is compatible with
standard industry platforms, such as CHO cells, CMV IE
promoters, commonly used plasmids, transfection/selection
agents, media etc.
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