Millipore Technical Publications |
 | AN- AN1672EN00 | |
Aqueous Solubility Testing with the MultiScreen HTS – PCF Filter Plate | ||
| Lit No: | AN1672EN00 | |
| Year: | 09/2008 | |
| Water solubility testing is an important part of many scientific studies, including the early drug discovery process. However, the standard shake-flask method for solubility testing is labor intensive and suited solely for low-throughput work. To overcome these challenges, Millipore has developed a new filtration-based assay using the MultiScreen<sub>HTS</sub> – PCF plate. This new solubility assay uses a high-throughput 96-well plate with a specially-developed membrane to improve particle retention and achieve reproducible results in the micromolar range. The plate is compatible with aqueous organic solutions (<10% DMSO) and both manual and automated systems. Click the PDF above for the full document. | |
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