Millipore Technical Publications |
 | DS- DS1043EN00 | |
AdenoSilence Adenoviral shRNA Expression Vector ReagentsTargeting the human druggable genome | ||
| Lit No: | DS1043EN00 | |
| Year: | 2007 | |
| Millipore’s new AdenoSilence product line includes adenoviral shRNA expression vectors for RNAi knockdown experiments. Adenosilence vectors will increase delivery efficiency and knockdown persistence in a wide array of targeted genes including all the major protein classes amenable to small molecule intervention. The use of replication incompetent vectors ensures that these are safe reagents for use in the lab. AdenoSilence vectors allow for single step delivery of shRNA through the direct application of the viral supernatants onto a primary cell culture, thereby making any additional transfection reagents or complex transfection protocols unnecessary. Human primary cells are the best systems to model disease and work well in target discovery programs reagents targeting the human druggable genome. Click the PDF above for the full document. | |
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