| Monitoring CD4+ and CD8+ T cell counts has become essential in research on blood from healthy individuals and immunodeficient patients such as those with HIV/AIDS. Most procedures for CD4+ and CD8+ T cell enumeration require the blood to be <48 hrs old for accurate results. This can often be a problem in resource-poor settings where samples need to be transported long distances for analysis due to a lack of instrumentation or operator availability. It has been reported that TransFix can stabilize blood for CD4+ T cell enumeration for up to 14 days. In this study, we demonstrate the compatibility of aged, TransFix-treated blood with the Guava EasyCD4™* and EasyCD8™* assays, which use low volumes of blood (10 μL/test) and have previously been found to provide accurate and precise results in multi-site studies compared to predicate methods. |
