 | One of the most important challenges the modern biotechnology faces is the reduction of costs associated with production of therapeutic recombinant proteins. These costs result from the long timelines necessary for generation of stable, highly productive cell lines. There are several steps identified as critical for protein expression which became targets for technological advancements. Traditionally, the transcription is considered to be the dominant factor controlling expression. However, posttranscriptional events can also affect protein production, modification and secretion.
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