Content Loading...
Content Loading...
Last Item Added: 0 Items
Content Loading...
» Close

Millipore Technical Publications


ps1113en00.pdf
PO- PS1113EN00

Assessment Of hERG Blockade By Radioligand Binding Assay With hERG Membrane Preparations

Lit No:PS1113EN00
Year:2008


Millipore provides a portfolio of solutions for evaluation of cardiac risk of candidate compounds:
  • CardiacProfilerTM Service is a comprehensive panel of assays for cardiac liability testing on candidate compounds.
  • For specific evaluation of hERG blocking activity of compounds, Millipore currently offers a panel of PrecisION® hERG cell lines developed in both HEK293 and CHO backgrounds (catalog # CYL 3006 and CYL3039 for hERG in HEK293 background, and CYL3038 for hERG in CHO background).
  • In addition, Millipore provides the hERGProfilerTM service for analysis of customer compounds with the PrecisION hERG cell lines, by validated methods including manual patch clamp, IonWorks® or PatchXpress® assays.
Click the PDF above for the full document.