Millipore Technical Publications |
 | TN- TB10140000 | |
Comparability between Mobius CellReady 3L Bioreactor and 3L glass bioreactors | ||
| Lit No: | TB10140000 | |
| Year: | 2009 | |
| Millipore’s Mobius CellReady 3L bioreactor is a single-use stirred tank bioreactor ideal for cell culture process development. Arriving pre-assembled and gamma irradiated, the CellReady 3L bioreactor significantly reduces the assembly time, down time and maintenance time associated with traditional glass bioreactors. To ensure maximum operational flexibility, the CellReady 3L bioreactor comes standard with pre-fitted weldable tubing lines, two available sparging options, a vent line, and integrated side sampling, addition, and drain ports. Designed to replace traditional bench-scale glass bioreactors, the CellReady 3L bioreactor is compatible with most standard controller configurations. To demonstrate comparable functionality, the 3L CellReady single-use bioreactor was evaluated against the 3L Applikon® glass bioreactor in head to head cell culture performance and vessel characterization experiments. The criteria examined in these experiments were CHO cell growth, viability, productivity, and the volumetric mass transfer coefficient for oxygen (kLa). For each of these criteria, the experimental results reported in this paper verify that the CellReady 3L bioreactor performs comparably and is suited to replace traditional glass. Click the PDF above for the full document. | |
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