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Millipore Technical Publications


tb1076en00.pdf
TN- TB1076EN00

Processing Economics of the Millipore Pod System Versus Millistak+ HC Lenticular Stacks

Lit No:TB1076EN00
Year:2007


Charged depth filters have been employed in biotech upstream clarification processes for decades. The particle capture mechanisms at work in charged depth filters are sieving, entrapment and adsorption, making them unique when compared to traditional membrane prefilters. Millipore improved the effectiveness of charged depth filters by introducing the multi layer Millistak+ HC media to the marketplace. The multi layer format requires fewer housings and compresses a multiple stage filtration process into a single step. The net effect for the end user is process compression, labor time savings, and ease of use.

Millipore now offers the Millistak+ HC charged depth filter media in a disposable format called the Pod. The Pod platform is a self-contained device that requires no housings. Because there are no large housings, the system volume of the Pod is approximately 20% less than the traditional lenticular stack format. With the Pod platform it is possible to have no product contact with the associated hardware, eliminating the need for clean in place (CIP) and the associated validation.


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