Millipore Technical Publications |
 | TN- TB1650EN00 | |
ProSep-vA Ultra Media 300 Cycle Lifetime Study | ||
| Lit No: | TB1650EN00 | |
| Year: | 2005 | |
| The selectivity, recovery and productivity benefits of protein A affinity chromatography now make it the most widely used technique for initial capture in the commercial purification of monoclonal antibodies (MAbs). While overall process economics are dependent on a number of factors, including buffer, utility, labor and capital depreciation costs, media cost can also have a significant impact. As protein A affinity resins are typically more expensive than other media, they may be viewed as less attractive for process selection. However, media cost is directly related to the lifetime of the resin and an extended resin lifetime may well compensate for a higher initial cost. Together with the other benefits of purity and yield, protein A resins can result in a favorable overall process cost and contribute to reduced cost of goods. This Technical Brief presents data on a study illustrating the extended lifetime capability for ProSep-vA Ultra resin. Click the PDF above for the full document. | |
| |
| |
