Millipore Technical Publications |
 | TN- TB2690EN00 | |
Lynx Sterile ConnectorsChoosing the Right Sterile Connector, Based on Design and Sterility Test Results | ||
| Lit No: | TB2690EN00 | |
| Year: | 2009 | |
| The Lynx S2S connector is a single use, single actuation device. It is comprised of a male and female coupling set designed to maintain sterility during the connection of two independent sterile fluid paths. Both units of the connector use a hose barb fitting to connect desired bags, containers or assemblies to the fluid path. Each fluid path is then sterilized by either gamma radiation, or by autoclave, in preparation for a sterile transfer of media, buffer or even final drug product. The connector’s process contact materials are constructed of high temperature gamma stable polysulfone with an over-molded silicone gasket, allowing for autoclaving up to 130°C for 30 minutes and/or gamma irradiation up to 45 kGy. The male and female coupling sets of the Lynx S2S connector uses solid plugs with silicone o-ring seals and gaskets for containment. This design provides high pressure sealing, and a tortuous path that assures zero passage of bacteria. After the couplings have been autoclaved and/or gamma irradiated, two sterilized assemblies can be connected by a series of simple steps in any environment. During the connection process, the plugs which will become contaminated in a non-classifed area, are isolated by moving them up and away from the fluid path within the female coupling body. This process assures a sterile fluid path (SAL of 10-6) for the liquid to flow through the connection. Click the PDF above for the full document. | |
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