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Millipore Technical Publications


00104755PU.pdf00104755PU.pdf
UG-00104755PU

Prosep® Ultra Plus Affinity Chromatography Media Operating Instructions

Lit No.:00104755PU
Rev No.:B
Year:2012
Rev Date:01/01/2012

Introduction

ProSep® Ultra Plus media has been developed specifically for industrial scale purification of monoclonal antibodies (MAbs). It facilitates the efficient, cost effective purification of MAbs. Its high capacity and excellent flow properties have been designed to address the needs of current and future higher titer feedstocks. Using clarified bioreactor feedstock at physiological pH and salt concentration, no pretreatment such as concentration by ultrafiltration or buffer exchange is required. This reduces time, labor and capital cost and improves retention of biological integrity of the antibody product

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